Zyban stop smoking reviews
- how effective is wellbutrin for quitting smoking
- how effective is bupropion for quitting smoking
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- how good is wellbutrin for quitting smoking
What happens if you smoke while taking bupropion...
How does bupropion work as a smoking cessation aid?
Bupropion exhibits reasonable efficacy as a smoking cessation aid, yet its precise mechanisms of action remain unclear.
Bupropion smoking cessation review
This review evaluates the mechanism of action of bupropion by considering the clinical evidence in combination with results from pre-clinical experiments in vivo and in vitro. Bupropion is a weak inhibitor of dopamine and noradrenaline reuptake, and has also been shown to antagonise nicotinic acetylcholine receptor function.
It is extensively metabolized in humans, its major metabolites reaching levels higher than those of bupropion itself. These metabolites share many of the pharmacological properties of bupropion, so they may play an important role in its clinical activity, yet they have been neglected in investigations into bupropion action.
This review led to several conclusions: (1) the principal mode of bupropion action is upon the withdrawal symptoms following smoking cessation; (2) during withdrawal, bupropion may attenuate symptoms by mimicking nicotinic effects on dopamine and noradrenaline; (3) it
- how effective is wellbutrin for smoking cessation
- how effective is bupropion for smoking cessation