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  • Bacille Calmette-Guérin (BCG) Vaccine for Tuberculosis

    About the Bacille Calmette-Guérin (BCG) Vaccine

    Bacille Calmette-Guérin (BCG) is a vaccine for tuberculosis (TB) disease.

    The vaccine is not generally used in the United States1 because of:

    • The low risk of infection with TB bacteria in the United States,
    • The variable effectiveness of the vaccine against adult pulmonary TB, and
    • The vaccine’s potential to cause a false-positive TB skin test reaction.

    Many people born outside the United States have been vaccinated with BCG.

    It is given to infants and small children in countries where TB is common. It protects children from getting severe forms of active TB disease, such as TB meningitis and miliary TB disease.

    For Everyone:Tuberculosis Vaccine

    BCG Vaccine and TB Testing

    The BCG vaccine may cause a false-positive TB skin test reaction.

    There is no reliable way to distinguish a positive TB skin test reaction caused by BCG vaccination from a reaction caused by true TB infection.

    TB blood tests (interferon-gamma release assay or IGRA) are the pr

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