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    Cephalexin


    Also known as Anhydrous cefalexin, Anhydrous cephalexin, Cefalexin, Cefalexin anhydrous, Cefalexina, Cefalexinum, Cephalexin anhydrous, Céfalexine, Keflex

    A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

    Cephalexin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

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    This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to second and third generation cephalosporins, cephalexin is more active against gram-positive and less active against gram-negative organisms.

    Originator: NCI Thesaurus | Source: The website of the National Cancer Institute (http://www.cancer.gov)

    Can I take Cephalexin while breastfeeding?

    Cephalexin is acceptable to use during breastfeeding.

    Limited information indicates that maternal doses of cephalexin up to 1 gram produce low levels in milk that are not expected to cause

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